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Global Opportunity

Back the Breakthrough. Redefine Treatment. With Us.

A once-in-a-generation opportunity to transform snakebite treatment globally

Global unmet need

A neglected market, ready for innovation

Snakebite envenoming is one of the most overlooked yet devastating medical emergencies of our time. Antivenom has barely changed in over a century, leaving millions of patients without access or adequate care.

First-in-Class, Differentiated Approach

Our oral combination therapy is designed to enable early intervention at the point of need, addressing critical limitations of existing antivenom-based care and positioned as a category-defining innovation.

Annually...

0M

Bites

0M

Serious cases

0K

Deaths

0K

Disabilities

Why now, why us

Six reasons to back Antigenika

Each pillar reinforces the next: a large unmet need, a differentiated approach, a credible foundation, a clear regulatory path, a scalable platform, and global alignment behind us

01
Market

Large, underserved market

A Global Crisis Without Modern Solutions

Global impact

5.4 million bites and 2.7 million serious envenomings each year, with venomous species present in more than 90% of countries globally

WHO recognition

Recognised by the WHO as a priority neglected tropical disease with dedicated 2030 targets to halve the global burden

02
Innovation

First-in-class, differentiated approach

Beyond Antivenom: Protecting Life & Limb

Breakthrough therapy

The first meaningful breakthrough in more than a century, with an oral combination therapy designed to enable early intervention at the point of need, addressing the critical limitations of antivenom-based care

Field-ready format

Oral, heat-stable format with no IV or cold-chain dependency, enabling immediate treatment in remote areas where 80% of bites occur

Broad-spectrum protection

Multi-pathway inhibition designed to work across medically significant species, solving the species-identification problem that limits current treatments

Tissue protection

Our approach targets tissue-destroying enzymes (metalloproteases and phospholipase A2), designed to prevent the lifelong disabilities that antivenom cannot address, with no existing product offering dual-site action

03
Foundation

Strong scientific and translational foundation

University of Reading Spin-Out Excellence

Research heritage

Built on research from the University of Reading and led by an internationally recognised venom pharmacologist and researchers with an expanding evidence base behind the lead programme

Robust mechanism

Robust mechanistic rationale targeting the most conserved and destructive pathways across snake venoms, validated through extensive preclinical work

Extensive coverage

Preclinical validation across 70+ venoms covering the major medically significant species responsible for global snakebite burden

Regulatory strategy

Clear regulatory strategy with accelerated clinical pathways due to the critical unmet medical need and orphan drug potential

04
Path to Market

Clear regulatory and commercial path

Clear regulatory path

Regulatory strategy

A defined regulatory strategy with strategic groundwork already underway in our priority launch regions, designed for rapid market penetration

Accelerated pathways

Defined regulatory pathways including accelerated approval opportunities through orphan drug designation and priority review mechanisms

India partnership

Strategic partnership in India supporting early market entry in the world's largest snakebite burden country with established distribution channels

Global rollout

Tiered expansion strategy designed to scale through LMICs where the burden is highest, then into developed markets to support global access and long-term sustainability

05
Platform

Scalable global platform

Scalable global platform

Global deployment

Designed from day one for global deployment, with manufacturing economics that support reach into the regions most affected

Manufacturing advantage

Low-cost, scalable small-molecule manufacturing enables affordable pricing for LMIC markets while maintaining strong margins needed to expand access globally

Platform expansion

Pipeline expansion into veterinary markets and adjacent toxin-related indications, creating multiple applications from the same core technology

IP position

Strong intellectual property portfolio around novel combinations and applications, with freedom to operate in key global markets

06
Alignment

Aligned with global health priorities

Creating Lasting Impact in Global Health

Global health agenda

Snakebite is a recognised priority neglected tropical disease, and our work sits squarely within an expanding global health agenda

WHO 2030 targets

Aligned with WHO 2030 targets to halve the global burden, with increasing government and NGO funding committed to snakebite solutions

Policy momentum

Growing policy focus through national snakebite strategies, particularly in high-burden countries like India, Nigeria, and Brazil

The Answer

Serpentium

A broad-spectrum, heat-stable, orally bioavailable therapy designed for the moment of bite, not the hospital ward.

IntravenousNo IV.
Cold-chain dependentNo cold chain.
Hospital-onlyNo hospital required.
Capability profile

Five design properties, each addressing a structural antivenom limitation

  • 01PHARMACOKINETICS

    Immediate intervention

    Addresses the pre-hospital window where 90% of mortality occurs

  • 02MECHANISM

    Broad-spectrum coverage

    Targets toxin classes, not species, for cross-protective effect

  • 03FORMULATION

    Oral, field-ready

    No injection, no IV line, no refrigeration. Stable at field temperatures

  • 04INDICATION

    Tissue protection

    Prevents the necrotic damage that drives permanent disability

  • 05MANUFACTURING

    Cost-effective at scale

    Small-molecule synthesis enables LMIC affordability with margin in developed markets

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