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The Science

A new generation of snakebite treatment

Our oral combination therapy is designed to work where existing antivenoms cannot, in the field, in the first hours after a bite

The Problem

Limitations of current treatment: Antivenom

Antivenom has barely changed since the 1890s. Its format limits where, when and for whom it works

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1
/ 05

IV-Only

Requires intravenous administration in clinical settings with cold-chain storage

2
/ 05

Species-Specific

Limited efficacy across different snake species

3
/ 05

Time-Sensitive

Treatment delays significantly reduce effectiveness

4
/ 05

No Tissue Protection

Cannot prevent or reverse local tissue damage causing lifelong disability

5
/ 05

High Cost

Manufacturing and administration expenses limit availability in affected regions

01 / 05
The Problem
Antivenom · since 1894
The Problem

Limitations of current treatment: Antivenom

Antivenom has barely changed since the 1890s. Its format limits where, when and for whom it works

IV-Only

Requires intravenous administration in clinical settings with cold-chain storage

Species-Specific

Limited efficacy across different snake species

Time-Sensitive

Treatment delays significantly reduce effectiveness

No Tissue Protection

Cannot prevent or reverse local tissue damage causing lifelong disability

High Cost

Manufacturing and administration expenses limit availability in affected regions

The Problem

Limitations of current treatment: Antivenom

Antivenom has barely changed since the 1890s. Its format limits where, when and for whom it works

01 / 05

IV-Only

Requires intravenous administration in clinical settings with cold-chain storage

02 / 05

Species-Specific

Limited efficacy across different snake species

03 / 05

Time-Sensitive

Treatment delays significantly reduce effectiveness

04 / 05

No Tissue Protection

Cannot prevent or reverse local tissue damage causing lifelong disability

05 / 05

High Cost

Manufacturing and administration expenses limit availability in affected regions

Our Universal Approach

Oral, heat-stable,
broad-spectrum

A heat-stable oral therapy can be stocked in clinics, pharmacies and field kits, and taken immediately after a bite. Broad-spectrum design means it is not limited to a single venom family.

  • 01Oral dosing, no injection or IV required
  • 02Heat-stable, no cold-chain dependency
  • 03Designed for broad coverage across medically significant species
  • 04Tissue protection that preserves muscle function and limits lifelong disability
Serpentium — Broad Spectrum Antivenom Combination Therapy
Inside the bloodstream

From bite to recovery, step by step

01 / Normal flow

A healthy blood vessel

Red blood cells flow smoothly through an intact vessel. The wall holds everything in place. The surrounding tissue is protected.

Red blood cells
Vessel wall
Venom enzymes
Serpentium
At the bite site

Protecting life and limb

01 / Muscle cells at the bite site

Healthy tissue, ready to move

Muscle fibres are packed together. Each cell is wrapped in a protective membrane, and the tissue structure is intact. This structure is what the venom will reach first, and this is what we need to protect.

Muscle cell
Nucleus
Tissue matrix
Venom enzymes
Serpentium

Supporting cell repair means muscle preservation and functional recovery

Where antivenom struggles, the local damage at the bite site, is exactly where Serpentium is designed to make the biggest difference. Surviving the bite shouldn't mean losing the limb.

0+

Venoms tested across medically significant species

Preclinical, broad spectrum
0K

People suffer permanent disabilities from snakebite each year

Annual global burden
0%

Of bite victims develop tissue damage that antivenom cannot address

Unmet clinical need

Covers the most medically significant snakes

Our oral therapy is designed to cover the venom families responsible for the majority of global envenomings, starting with the four species that cause the highest burden in India

Russell's Viper

Russell's Viper

South Asia
Indian Cobra

Indian Cobra

South Asia
Common Krait

Common Krait

South Asia
Saw-scaled Viper

Saw-scaled Viper

Africa & Asia
Puff Adder

Puff Adder

Sub-Saharan Africa
European Adder

European Adder

Europe
Western Diamondback

Western Diamondback

North America
Common Lancehead

Common Lancehead

Latin America
Broad-banded Copperhead

Broad-banded Copperhead

North America
Cantil Viper

Cantil Viper

Central America
Western Cottonmouth

Western Cottonmouth

North America
Gaboon Viper

Gaboon Viper

Central Africa
Butterfly Viper

Butterfly Viper

West Africa
Banded Cobra

Banded Cobra

Southern Africa
Timber Rattlesnake

Timber Rattlesnake

North America
Egyptian Cobra

Egyptian Cobra

North Africa
Horned Viper

Horned Viper

North Africa & Middle East
Coastal Taipan

Coastal Taipan

Oceania
Mozambique Spitting Cobra

Mozambique Spitting Cobra

Southern Africa
Mangrove Pit Viper

Mangrove Pit Viper

Southeast Asia
Russell's Viper

Russell's Viper

South Asia
Indian Cobra

Indian Cobra

South Asia
Common Krait

Common Krait

South Asia
Saw-scaled Viper

Saw-scaled Viper

Africa & Asia
Puff Adder

Puff Adder

Sub-Saharan Africa
European Adder

European Adder

Europe
Western Diamondback

Western Diamondback

North America
Common Lancehead

Common Lancehead

Latin America
Broad-banded Copperhead

Broad-banded Copperhead

North America
Cantil Viper

Cantil Viper

Central America
Western Cottonmouth

Western Cottonmouth

North America
Gaboon Viper

Gaboon Viper

Central Africa
Butterfly Viper

Butterfly Viper

West Africa
Banded Cobra

Banded Cobra

Southern Africa
Timber Rattlesnake

Timber Rattlesnake

North America
Egyptian Cobra

Egyptian Cobra

North Africa
Horned Viper

Horned Viper

North Africa & Middle East
Coastal Taipan

Coastal Taipan

Oceania
Mozambique Spitting Cobra

Mozambique Spitting Cobra

Southern Africa
Mangrove Pit Viper

Mangrove Pit Viper

Southeast Asia
Indication

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